Groundbreaking Cancer Metabolism Discovery by HealthieOne's Lead Scientist

HealthieOne lead scientist Dr. Anne Le, during her tenure time at Johns Hopkins, made a groundbreaking discovery that cancer cells can survive and replicate using alternative metabolic pathways beyond glucose. Her team's research, published in Cell Metabolism, revealed that lymph gland cancer B cells can use glutamine as an energy source in the absence of glucose for cell replication and survival, particularly under low-oxygen conditions common in tumors. This critical finding provided evidence that lymphoma cancer growth could be accomplished by inhibiting glutaminase, a glutamine enzyme, opening new avenues for innovative cancer therapies targeting tumor metabolism. Dr. Le's pioneering work in understanding cancer cell metabolism flexibility continues to influence her approach to developing HealthieOne's comprehensive metabolic testing solutions.