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Dehydroepiandrosterone sulfate

Dehydroepiandrosterone sulfate

Explanation: Dehydroepiandrosterone sulfate (DHEA-S) is a form of DHEA, a hormone made by the adrenal glands (small glands on top of the kidneys) and the reproductive gland. DHEA-S is a "precursor hormone", meaning the body uses it to make other hormones like androgens and estrogens. DHEA plays a role in energy levels, mood, stress, bone strength, and the development of male and female traits and reproductive health. DHEA-S levels are highest in early adulthood and naturally decrease as you age.

Test purpose:

  • Detect hormone imbalances: High or low levels may indicate conditions like adrenal hyperplasia, polycystic ovary syndrome (PCOS).
  • Investigate symptoms: Such as excessive hair growth (hirsutism), irregular periods, or infertility; helps identify problems related to the adrenal glands, reproductive health, and hormone production.
  • Monitor aging or stress-related changes: Since DHEA levels naturally decline with age, the test shows how your level compares with the usual range for your age and sex, and older adults whose DHEA-S level dropped steeply over several years had a higher risk of death.
  • For individuals on DHEA supplements, blood tests can monitor hormone levels to ensure they are within a therapeutic range and to adjust dosage if necessary.

Other information about this test:Mayo Clinic, MedlinePlus, UCSF Health, Cleveland Clinic, ARUP Laboratories

An aspect of Female Health.
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