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Coproporphyrin I
Coproporphyrin I
Explanation: Coproporphyrin I is one of the substances called porphyrins which are involved in the production of heme, which is a key component of hemoglobin, the molecule in red blood cells that carries oxygen. However, coproporphyrin I is not typically part of the normal heme synthesis pathway; healthy people also make small amounts of it as a side product, and high levels can point to enzyme deficiencies or genetic mutations affecting porphyrin metabolism.
Test purpose:
- Detect porphyria: Porphyria is a group of rare genetic disorders that affect the production of heme, leading to porphyrin buildup. This test is often performed when someone has symptoms like abdominal pain, skin sensitivity to sunlight, dark urine, or neurological issues, which are common in porphyria.
- Evaluate liver function: High levels may suggest issues with bile flow or liver diseases.
Other information about this test: UCSF Health, MedlinePlus
An aspect of Liver and Pancreas Health.