What are these lipoprotein tests?

LDL (Low-Density Lipoprotein) Subfractions:

  • LDL Particle Number (LDL-P): Total count of LDL particles
  • LDL Size/Peak Size: Average diameter of LDL particles
  • LDL Pattern: Classification as Pattern A (large, buoyant) or Pattern B (small, dense)
  • LDL Small/Medium: Concentration of specific LDL subclasses

HDL (High-Density Lipoprotein) Subfractions:

  • HDL-P: Total HDL particle count
  • HDL Size: Average HDL particle diameter
  • HDL Large: Concentration of large HDL particles

VLDL (Very Low-Density Lipoprotein) Subfractions:

  • Large VLDL-P: Count of large VLDL particles
  • VLDL Size: Average VLDL particle diameter

Do particle size or number results change my treatment?

No. Knowing your LDL/HDL/VLDL particle sizes or numbers rarely changes what your doctor will recommend.

Whether you have Pattern A (large, buoyant) or Pattern B (small, dense) LDL particles, the treatment approach remains the same:

  • Lifestyle modifications (diet, exercise, weight management)
  • Statin therapy when indicated based on overall cardiovascular risk
  • LDL-C lowering remains the primary target

References