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Cortisol/Dehydroepiandrosterone sulfate (DHEA-S) Ratio

Looking for an easy way to test and monitor your Cortisol/Dehydroepiandrosterone sulfate (DHEA-S) Ratio?
It's included in the HealthieOne Complete test.

Cortisol/Dehydroepiandrosterone sulfate (DHEA-S) Ratio

Explanation: The Cortisol/Dehydroepiandrosterone sulfate (DHEA-S) Ratio captures the balance between your body's primary stress hormone and its major anabolic-protective counterpart. Cortisol is released by the adrenal glands in response to stress, raising blood sugar, suppressing immune function, and breaking down muscle and bone when chronically elevated. DHEA-S (dehydroepiandrosterone sulfate) is also produced by the adrenals but exerts opposing effects: supporting immune function, building tissue, protecting the brain, and buffering cortisol's catabolic impact. Both hormones derive from the same precursor, so this ratio reflects how your adrenal glands allocate resources between stress response and restoration.

Test purpose:

  • Assess adrenal stress response and resilience: Reveals whether your adrenal output favors catabolic stress hormones over protective anabolic hormones, indicating chronic stress burden and diminished recovery capacity.

Note: Universal clinical reference ranges have not been established for this calculated marker. Available cutoffs vary by population and clinical context. This value should be interpreted alongside individual component values, clinical history, and other relevant biomarkers.

An aspect of Resilience and Longevity.

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